I was sidelined for like a week and a half so badly even Immodium couldn't help after I got back from Morocco in September. Still had a great time, still recommend it, but man am I glad I was back home before it hit me! That would not have been a fun 20 hours of travel back home...
Well, I was prescribed Cipro (only to be used in an emergency, I didn't actually ever take it) if that tells ya anything.
For those than don't know, Cipro is an incredibly power antibiotic generally used only in life-threatening situations. It'll basically cure you of any infection, except you'll get even sicker with every possible side-effect known to man for several days first. Also, sometimes you just die anyway.